Proteomics of protein trafficking by in vivo tissue-specific labeling

Conventional approaches to identify secreted factors that regulate homeostasis are limited in their abilities to identify the tissues/cells of origin and destination. We established a platform to identify secreted protein trafficking between organs using an engineered biotin ligase (BirA*G3) that bi...

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Detalles Bibliográficos
Autores principales: Droujinine, Ilia A., Meyer, Amanda S., Wang, Dan, Udeshi, Namrata D., Hu, Yanhui, Rocco, David, McMahon, Jill A., Yang, Rui, Guo, JinJin, Mu, Luye, Carey, Dominique K., Svinkina, Tanya, Zeng, Rebecca, Branon, Tess, Tabatabai, Areya, Bosch, Justin A., Asara, John M., Ting, Alice Y., Carr, Steven A., McMahon, Andrew P., Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062696/
https://www.ncbi.nlm.nih.gov/pubmed/33888706
http://dx.doi.org/10.1038/s41467-021-22599-x

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