The mTOR Deficiency in Monocytic Myeloid-Derived Suppressor Cells Protects Mouse Cardiac Allografts by Inducing Allograft Tolerance

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) can prevent allograft rejection and induce immune tolerance in transplantation models. Previous studies have demonstrated that inhibition of mTOR signaling can enhance the MDSC protective effect in heart transplantation (HTx) by promoting MDSC exp...

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Detalles Bibliográficos
Autores principales: Li, Jiawei, Chen, Juntao, Zhang, Mingnan, Zhang, Chao, Wu, Renyan, Yang, Tianying, Qiu, Yue, Liu, Jingjing, Zhu, Tongyu, Zhang, Yi, Rong, Ruiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062712/
https://www.ncbi.nlm.nih.gov/pubmed/33897705
http://dx.doi.org/10.3389/fimmu.2021.661338

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