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High Dose IFN-β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells

Interferon β (IFN-β) signaling activates the transcription factor complex ISGF3 to induce gene expression programs critical for antiviral defense and host immune responses. It has also been observed that IFN-β activates a second transcription factor complex, γ-activated factor (GAF), but the signifi...

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Detalles Bibliográficos
Autores principales:	Kishimoto, Kensei, Wilder, Catera L., Buchanan, Justin, Nguyen, Minh, Okeke, Chidera, Hoffmann, Alexander, Cheng, Quen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062733/ https://www.ncbi.nlm.nih.gov/pubmed/33897699 http://dx.doi.org/10.3389/fimmu.2021.651254

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