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Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes

Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate g...

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Detalles Bibliográficos
Autores principales: Kamruzzaman, Md, Horowitz, Michael, Jones, Karen L., Marathe, Chinmay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062751/
https://www.ncbi.nlm.nih.gov/pubmed/33897622
http://dx.doi.org/10.3389/fendo.2021.661877
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author Kamruzzaman, Md
Horowitz, Michael
Jones, Karen L.
Marathe, Chinmay S.
author_facet Kamruzzaman, Md
Horowitz, Michael
Jones, Karen L.
Marathe, Chinmay S.
author_sort Kamruzzaman, Md
collection PubMed
description Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate gastrointestinal function, particularly by slowing gastric emptying and/or stimulating incretin hormone GLP-1, are summarized in this review.
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spelling pubmed-80627512021-04-24 Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes Kamruzzaman, Md Horowitz, Michael Jones, Karen L. Marathe, Chinmay S. Front Endocrinol (Lausanne) Endocrinology Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate gastrointestinal function, particularly by slowing gastric emptying and/or stimulating incretin hormone GLP-1, are summarized in this review. Frontiers Media S.A. 2021-04-09 /pmc/articles/PMC8062751/ /pubmed/33897622 http://dx.doi.org/10.3389/fendo.2021.661877 Text en Copyright © 2021 Kamruzzaman, Horowitz, Jones and Marathe https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Kamruzzaman, Md
Horowitz, Michael
Jones, Karen L.
Marathe, Chinmay S.
Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes
title Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes
title_full Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes
title_fullStr Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes
title_full_unstemmed Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes
title_short Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes
title_sort gut-based strategies to reduce postprandial glycaemia in type 2 diabetes
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062751/
https://www.ncbi.nlm.nih.gov/pubmed/33897622
http://dx.doi.org/10.3389/fendo.2021.661877
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