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Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection
How helminths influence the pathogenesis of sexually transmitted viral infections is not comprehensively understood. Here, we show that an acute helminth infection (Nippostrongylus brasiliensis [Nb]) induced a type 2 immune profile in the female genital tract (FGT). This leads to heightened epitheli...
Autores principales: | Chetty, Alisha, Darby, Matthew G., Vornewald, Pia M., Martín-Alonso, Mara, Filz, Anna, Ritter, Manuel, McSorley, Henry J., Masson, Lindi, Smith, Katherine, Brombacher, Frank, O’Shea, Matthew K., Cunningham, Adam F., Ryffel, Bernhard, Oudhoff, Menno J., Dewals, Benjamin G., Layland, Laura E., Horsnell, William G.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062792/ https://www.ncbi.nlm.nih.gov/pubmed/33857419 http://dx.doi.org/10.1016/j.chom.2021.02.004 |
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