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Iron-withdrawing anti-infectives for new host-directed therapies based on iron dependence, the Achilles’ heel of antibiotic-resistant microbes

The iron dependence of antibiotic-resistant microbes represents an Achilles’ heel that can be exploited broadly. The growing global problem of antibiotic resistance of microbial pathogens wherein microbes become resistant to the very antibiotics used against them during infection is linked not only...

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Detalles Bibliográficos
Autores principales: Holbein, Bruce E., Ang, M. Trisha C., Allan, David S., Chen, Wangxue, Lehmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062846/
https://www.ncbi.nlm.nih.gov/pubmed/33907538
http://dx.doi.org/10.1007/s10311-021-01242-7