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Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development
Osteoarthritis (OA) is a degenerative joint disease with multiple etiologies that affects individuals worldwide. No effective interventions are currently available to reverse the pathological process of OA. Sodium butyrate (NaB), a component of short-chain fatty acids (SCFAs), has multiple biologica...
Autores principales: | Zhou, Haikang, Li, Guoqing, Wang, Yang, Jiang, Rendong, Li, Yicheng, Wang, Huhu, Wang, Fei, Ma, Hairong, Cao, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062861/ https://www.ncbi.nlm.nih.gov/pubmed/33897442 http://dx.doi.org/10.3389/fphar.2021.659597 |
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