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Tonic Control of Secretory Acid Sphingomyelinase Over Ventral Hippocampal Synaptic Transmission and Neuron Excitability

The acid sphingomyelinase (ASM) converts sphingomyelin into ceramide. Recent work has advanced the ASM/ceramide system as a major player in the pathogenesis of major depressive disorder (MDD). Indeed, ASM activity is enhanced in MDD patients and antidepressant drugs like fluoxetine act as functional...

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Detalles Bibliográficos
Autores principales:	Lin, Chih-Hung, Kornhuber, Johannes, Zheng, Fang, Alzheimer, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062921/ https://www.ncbi.nlm.nih.gov/pubmed/33897374 http://dx.doi.org/10.3389/fncel.2021.660561

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