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Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma
Intratumoral drug delivery is a promising approach for the treatment of glioblastoma multiforme (GBM). However, drug washout remains a major challenge in GBM therapy. Our strategy, aimed at reducing drug clearance and enhancing site-specific residence time, involves the local administration of a mul...
Autores principales: | Brachi, Giulia, Ruiz-Ramírez, Javier, Dogra, Prashant, Wang, Zhihui, Cristini, Vittorio, Ciardelli, Gianluca, Rostomily, Robert C., Ferrari, Mauro, Mikheev, Andrei M., Blanco, Elvin, Mattu, Clara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062960/ https://www.ncbi.nlm.nih.gov/pubmed/33237080 http://dx.doi.org/10.1039/d0nr05053a |
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