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MutSα mismatch repair protein stability is governed by subunit interaction, acetylation, and ubiquitination

In eukaryotes, DNA mismatch recognition is accomplished by the highly conserved MutSα (Msh2/Msh6) and MutSβ (Msh2/Msh3) complexes. Previously, in the yeast Saccharomyces cerevisiae, we determined that deleting MSH6 caused wild-type Msh2 levels to drop by ∼50%. In this work, we determined that Msh6 s...

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Detalles Bibliográficos
Autores principales:	Arlow, Tim, Kim, Junwon, Haye-Bertolozzi, Joanna E., Martínez, Cristina Balbás, Fay, Caitlin, Zorensky, Emma, Rose, Mark D., Gammie, Alison E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063085/ https://www.ncbi.nlm.nih.gov/pubmed/33793773 http://dx.doi.org/10.1093/g3journal/jkaa065

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