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Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs

Human sterile alpha motif and HD-domain-containing protein 1 (SAMHD1) has been identified as a GTP or dGTP-dependent deoxynucleotide triphosphohydrolase (dNTPase) and acts as an antiviral factor against certain retroviruses and DNA viruses. Genetic mutation in SAMHD1 causes the inflammatory Aicardi-...

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Detalles Bibliográficos
Autores principales:	Chen, Zhangming, Hu, Jie, Ying, Songcheng, Xu, Aman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063254/ https://www.ncbi.nlm.nih.gov/pubmed/33907561 http://dx.doi.org/10.3892/ol.2021.12712

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