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Mild traumatic brain injury induces microvascular injury and accelerates Alzheimer-like pathogenesis in mice
INTRODUCTION: Traumatic brain injury (TBI) is considered as the most robust environmental risk factor for Alzheimer’s disease (AD). Besides direct neuronal injury and neuroinflammation, vascular impairment is also a hallmark event of the pathological cascade after TBI. However, the vascular connecti...
Autores principales: | Wu, Yingxi, Wu, Haijian, Zeng, Jianxiong, Pluimer, Brock, Dong, Shirley, Xie, Xiaochun, Guo, Xinying, Ge, Tenghuan, Liang, Xinyan, Feng, Sudi, Yan, Youzhen, Chen, Jian-Fu, Sta Maria, Naomi, Ma, Qingyi, Gomez-Pinilla, Fernando, Zhao, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063402/ https://www.ncbi.nlm.nih.gov/pubmed/33892818 http://dx.doi.org/10.1186/s40478-021-01178-7 |
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