A dual-targeting ruthenium nanodrug that inhibits primary tumor growth and lung metastasis via the PARP/ATM pathway

BACKGROUND: Many studies have found that ruthenium complexes possess unique biochemical characteristics and inhibit tumor growth or metastasis. RESULTS: Here, we report the novel dual-targeting ruthenium candidate 2b, which has both antitumor and antimetastatic properties and targets tumor sites thr...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yu, Zhu, Di, Gui, Lin, Li, Yuanming, Wang, Wenjing, Liu, Jiawang, Wang, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063440/
https://www.ncbi.nlm.nih.gov/pubmed/33892746
http://dx.doi.org/10.1186/s12951-021-00799-3

Ejemplares similares

Ejemplares similares