Cargando…
Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021
SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063588/ https://www.ncbi.nlm.nih.gov/pubmed/33890568 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.16.2100413 |
| _version_ | 1783681976465620992 |
|---|---|
| author | Jungnick, Sabrina Hobmaier, Bernhard Mautner, Lena Hoyos, Mona Haase, Maren Baiker, Armin Lahne, Heidi Eberle, Ute Wimmer, Clara Hepner, Sabrina Sprenger, Annika Berger, Carola Dangel, Alexandra Wildner, Manfred Liebl, Bernhard Ackermann, Nikolaus Sing, Andreas Fingerle, Volker Bartha-Dima, Bernadett Bengs, Katja Berger, Anja Boll, Kerstin Carl, Anja Jürgen, Christian Drdlicek, Juliana Eisenberger, David Flechsler, Jennifer Gerdes, Lars Githure, George Govindaswamy, Janani Hupfer, Christine Konrad, Regina Lupoli, Gaia Lutmayr, Johannes Margos, Gabriele Müller, Roswitha Nickel, Silke Okeyo, Mercy Pavlovic, Melanie Pecoraro, Sven Sahm, Isabel Schauer, Melanie Schülein, Anika Schürmann, Eva-Maria Schulze, Gesine Scuda, Nelly Singer, Stefanie Stellberger, Thorsten Treis, Bianca Tuschak, Christian Zimmermann, Pia Paravinja, Natali |
| author_facet | Jungnick, Sabrina Hobmaier, Bernhard Mautner, Lena Hoyos, Mona Haase, Maren Baiker, Armin Lahne, Heidi Eberle, Ute Wimmer, Clara Hepner, Sabrina Sprenger, Annika Berger, Carola Dangel, Alexandra Wildner, Manfred Liebl, Bernhard Ackermann, Nikolaus Sing, Andreas Fingerle, Volker Bartha-Dima, Bernadett Bengs, Katja Berger, Anja Boll, Kerstin Carl, Anja Jürgen, Christian Drdlicek, Juliana Eisenberger, David Flechsler, Jennifer Gerdes, Lars Githure, George Govindaswamy, Janani Hupfer, Christine Konrad, Regina Lupoli, Gaia Lutmayr, Johannes Margos, Gabriele Müller, Roswitha Nickel, Silke Okeyo, Mercy Pavlovic, Melanie Pecoraro, Sven Sahm, Isabel Schauer, Melanie Schülein, Anika Schürmann, Eva-Maria Schulze, Gesine Scuda, Nelly Singer, Stefanie Stellberger, Thorsten Treis, Bianca Tuschak, Christian Zimmermann, Pia Paravinja, Natali |
| author_sort | Jungnick, Sabrina |
| collection | PubMed |
| description | SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were respectively diluted both in DMEM and saliva. Dilutions were analysed with Roche, Siemens, Abbott, nal von minden and RapiGEN RATs. While further studies with appropriate real-life clinical samples are warranted, all RATs detected B.1.1.7 and B.1.351, generally comparable to non-VOC strain. |
| format | Online Article Text |
| id | pubmed-8063588 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | European Centre for Disease Prevention and Control (ECDC) |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-80635882021-04-27 Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 Jungnick, Sabrina Hobmaier, Bernhard Mautner, Lena Hoyos, Mona Haase, Maren Baiker, Armin Lahne, Heidi Eberle, Ute Wimmer, Clara Hepner, Sabrina Sprenger, Annika Berger, Carola Dangel, Alexandra Wildner, Manfred Liebl, Bernhard Ackermann, Nikolaus Sing, Andreas Fingerle, Volker Bartha-Dima, Bernadett Bengs, Katja Berger, Anja Boll, Kerstin Carl, Anja Jürgen, Christian Drdlicek, Juliana Eisenberger, David Flechsler, Jennifer Gerdes, Lars Githure, George Govindaswamy, Janani Hupfer, Christine Konrad, Regina Lupoli, Gaia Lutmayr, Johannes Margos, Gabriele Müller, Roswitha Nickel, Silke Okeyo, Mercy Pavlovic, Melanie Pecoraro, Sven Sahm, Isabel Schauer, Melanie Schülein, Anika Schürmann, Eva-Maria Schulze, Gesine Scuda, Nelly Singer, Stefanie Stellberger, Thorsten Treis, Bianca Tuschak, Christian Zimmermann, Pia Paravinja, Natali Euro Surveill Rapid Communication SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were respectively diluted both in DMEM and saliva. Dilutions were analysed with Roche, Siemens, Abbott, nal von minden and RapiGEN RATs. While further studies with appropriate real-life clinical samples are warranted, all RATs detected B.1.1.7 and B.1.351, generally comparable to non-VOC strain. European Centre for Disease Prevention and Control (ECDC) 2021-04-22 /pmc/articles/PMC8063588/ /pubmed/33890568 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.16.2100413 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
| spellingShingle | Rapid Communication Jungnick, Sabrina Hobmaier, Bernhard Mautner, Lena Hoyos, Mona Haase, Maren Baiker, Armin Lahne, Heidi Eberle, Ute Wimmer, Clara Hepner, Sabrina Sprenger, Annika Berger, Carola Dangel, Alexandra Wildner, Manfred Liebl, Bernhard Ackermann, Nikolaus Sing, Andreas Fingerle, Volker Bartha-Dima, Bernadett Bengs, Katja Berger, Anja Boll, Kerstin Carl, Anja Jürgen, Christian Drdlicek, Juliana Eisenberger, David Flechsler, Jennifer Gerdes, Lars Githure, George Govindaswamy, Janani Hupfer, Christine Konrad, Regina Lupoli, Gaia Lutmayr, Johannes Margos, Gabriele Müller, Roswitha Nickel, Silke Okeyo, Mercy Pavlovic, Melanie Pecoraro, Sven Sahm, Isabel Schauer, Melanie Schülein, Anika Schürmann, Eva-Maria Schulze, Gesine Scuda, Nelly Singer, Stefanie Stellberger, Thorsten Treis, Bianca Tuschak, Christian Zimmermann, Pia Paravinja, Natali Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 |
| title | Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 |
| title_full | Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 |
| title_fullStr | Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 |
| title_full_unstemmed | Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 |
| title_short | Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021 |
| title_sort | detection of the new sars-cov-2 variants of concern b.1.1.7 and b.1.351 in five sars-cov-2 rapid antigen tests (rats), germany, march 2021 |
| topic | Rapid Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063588/ https://www.ncbi.nlm.nih.gov/pubmed/33890568 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.16.2100413 |
| work_keys_str_mv | AT jungnicksabrina detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT hobmaierbernhard detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT mautnerlena detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT hoyosmona detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT haasemaren detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT baikerarmin detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT lahneheidi detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT eberleute detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT wimmerclara detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT hepnersabrina detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT sprengerannika detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT bergercarola detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT dangelalexandra detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT wildnermanfred detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT lieblbernhard detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT ackermannnikolaus detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT singandreas detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT fingerlevolker detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT barthadimabernadett detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT bengskatja detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT bergeranja detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT bollkerstin detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT carlanja detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT jurgenchristian detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT drdlicekjuliana detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT eisenbergerdavid detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT flechslerjennifer detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT gerdeslars detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT githuregeorge detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT govindaswamyjanani detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT hupferchristine detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT konradregina detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT lupoligaia detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT lutmayrjohannes detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT margosgabriele detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT mullerroswitha detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT nickelsilke detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT okeyomercy detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT pavlovicmelanie detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT pecorarosven detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT sahmisabel detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT schauermelanie detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT schuleinanika detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT schurmannevamaria detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT schulzegesine detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT scudanelly detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT singerstefanie detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT stellbergerthorsten detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT treisbianca detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT tuschakchristian detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT zimmermannpia detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 AT paravinjanatali detectionofthenewsarscov2variantsofconcernb117andb1351infivesarscov2rapidantigentestsratsgermanymarch2021 |