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Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts

Congenital heart defects are the most common birth defect and have a clear genetic component, yet genomic structural variations or gene mutations account for only a third of the cases. Epigenomic dynamics during human heart organogenesis thus may play a critical role in regulating heart development....

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Detalles Bibliográficos
Autores principales: Chen, Fengling, Chen, Jiewen, Wang, Hong, Tang, Huayuan, Huang, Lei, Wang, Shijia, Wang, Xinru, Fang, Xi, Liu, Jie, Li, Li, Ouyang, Kunfu, Han, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063616/
https://www.ncbi.nlm.nih.gov/pubmed/33898448
http://dx.doi.org/10.3389/fcell.2021.651655