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Loss of Speckle-Type POZ Protein Promotes Prostate Cancer Cell Migration and Invasion Through Upregulation of MCP-1

BACKGROUND: The goal of this study is to verify that the loss of speckle-type POZ protein (SPOP) promotes the migration and invasion of prostate cancer cells, and that this process is brought about by an increase in MCP-1. MATERIAL/METHODS: SPOP knockout C4-2 cells (C4-2 SPOP(−/−)) were verified by...

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Detalles Bibliográficos
Autores principales: Shi, Junlin, Cao, Ji, Lu, Xiaomei, Fan, Langlin, Guo, Hongwei, Fu, Jiejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063634/
https://www.ncbi.nlm.nih.gov/pubmed/33872295
http://dx.doi.org/10.12659/MSM.929199

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