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SynBiopython: an open-source software library for Synthetic Biology

Advances in hardware automation in synthetic biology laboratories are not yet fully matched by those of their software counterparts. Such automated laboratories, now commonly called biofoundries, require software solutions that would help with many specialized tasks such as batch DNA design, sample...

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Detalles Bibliográficos
Autores principales: Yeoh, Jing Wui, Swainston, Neil, Vegh, Peter, Zulkower, Valentin, Carbonell, Pablo, Holowko, Maciej B, Peddinti, Gopal, Poh, Chueh Loo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063678/
http://dx.doi.org/10.1093/synbio/ysab001
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author Yeoh, Jing Wui
Swainston, Neil
Vegh, Peter
Zulkower, Valentin
Carbonell, Pablo
Holowko, Maciej B
Peddinti, Gopal
Poh, Chueh Loo
author_facet Yeoh, Jing Wui
Swainston, Neil
Vegh, Peter
Zulkower, Valentin
Carbonell, Pablo
Holowko, Maciej B
Peddinti, Gopal
Poh, Chueh Loo
author_sort Yeoh, Jing Wui
collection PubMed
description Advances in hardware automation in synthetic biology laboratories are not yet fully matched by those of their software counterparts. Such automated laboratories, now commonly called biofoundries, require software solutions that would help with many specialized tasks such as batch DNA design, sample and data tracking, and data analysis, among others. Typically, many of the challenges facing biofoundries are shared, yet there is frequent wheel-reinvention where many labs develop similar software solutions in parallel. In this article, we present the first attempt at creating a standardized, open-source Python package. A number of tools will be integrated and developed that we envisage will become the obvious starting point for software development projects within biofoundries globally. Specifically, we describe the current state of available software, present usage scenarios and case studies for common problems, and finally describe plans for future development. SynBiopython is publicly available at the following address: http://synbiopython.org.
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spelling pubmed-80636782021-04-29 SynBiopython: an open-source software library for Synthetic Biology Yeoh, Jing Wui Swainston, Neil Vegh, Peter Zulkower, Valentin Carbonell, Pablo Holowko, Maciej B Peddinti, Gopal Poh, Chueh Loo Synth Biol (Oxf) Software Advances in hardware automation in synthetic biology laboratories are not yet fully matched by those of their software counterparts. Such automated laboratories, now commonly called biofoundries, require software solutions that would help with many specialized tasks such as batch DNA design, sample and data tracking, and data analysis, among others. Typically, many of the challenges facing biofoundries are shared, yet there is frequent wheel-reinvention where many labs develop similar software solutions in parallel. In this article, we present the first attempt at creating a standardized, open-source Python package. A number of tools will be integrated and developed that we envisage will become the obvious starting point for software development projects within biofoundries globally. Specifically, we describe the current state of available software, present usage scenarios and case studies for common problems, and finally describe plans for future development. SynBiopython is publicly available at the following address: http://synbiopython.org. Oxford University Press 2021-02-22 /pmc/articles/PMC8063678/ http://dx.doi.org/10.1093/synbio/ysab001 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Yeoh, Jing Wui
Swainston, Neil
Vegh, Peter
Zulkower, Valentin
Carbonell, Pablo
Holowko, Maciej B
Peddinti, Gopal
Poh, Chueh Loo
SynBiopython: an open-source software library for Synthetic Biology
title SynBiopython: an open-source software library for Synthetic Biology
title_full SynBiopython: an open-source software library for Synthetic Biology
title_fullStr SynBiopython: an open-source software library for Synthetic Biology
title_full_unstemmed SynBiopython: an open-source software library for Synthetic Biology
title_short SynBiopython: an open-source software library for Synthetic Biology
title_sort synbiopython: an open-source software library for synthetic biology
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063678/
http://dx.doi.org/10.1093/synbio/ysab001
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