Optimized experimental pre-treatment strategy for temporary inhibition of islet amyloid polypeptide aggregation

Islet amyloid polypeptide (IAPP) is a neuroendocrine hormone from pancreatic β-cells. Misfolded, aggregated IAPP is believed to be toxic to islet cells and amyloid deposits in the pancreas are pathological hallmarks of type 2 diabetes. Rapid fibrillization of this peptide makes it difficult to study...

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Detalles Bibliográficos
Autores principales: Ferguson, Madison Q., DeRosa, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063701/
https://www.ncbi.nlm.nih.gov/pubmed/33912690
http://dx.doi.org/10.1016/j.bbrep.2021.100964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063701/
https://www.ncbi.nlm.nih.gov/pubmed/33912690
http://dx.doi.org/10.1016/j.bbrep.2021.100964

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