Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis

Epilepsy associated with Rasmussen’s encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating conseq...

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Detalles Bibliográficos
Autores principales: Feyissa, Anteneh M., Mohamed, Alaa S., Tatum, William O., Campbell, Alana S., Lopez-Chiriboga, A. Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063734/
https://www.ncbi.nlm.nih.gov/pubmed/33912823
http://dx.doi.org/10.1016/j.ebr.2021.100445
Descripción
Sumario:Epilepsy associated with Rasmussen’s encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outcome of a 32-year-old woman with adult-onset Rasmussen’s, who was treated with brain-responsive neurostimulation (RNS) after failure of several immunotherapeutic and anti-seizure medications.

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