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Simvastatin inhibits POVPC-mediated induction of endothelial-to-mesenchymal cell transition

Endothelial-to-mesenchymal transition (EndMT), the process by which an endothelial cell (EC) undergoes a series of molecular events that result in a mesenchymal cell phenotype, plays an important role in atherosclerosis. 1-Palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC), derived from...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Yi-Xin, Ning, Da-Sheng, Chen, Jing, Li, Shang-Xuan, Mo, Zhi-Wei, Peng, Yue-Ming, He, Shi-Hui, Chen, Ya-Ting, Zheng, Chun-Juan, Gao, Jian-Jun, Yuan, Hao-Xiang, Ou, Jing-Song, Ou, Zhi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063863/
https://www.ncbi.nlm.nih.gov/pubmed/33711324
http://dx.doi.org/10.1016/j.jlr.2021.100066

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