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Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model

Globus pallidus externa (GPe) is a nucleus in the basal ganglia circuitry involved in the control of movement. Recent studies have demonstrated a critical role of GPe cell types in Parkinsonism. Specifically increasing the function of parvalbumin (PV) neurons in the GPe has been found to facilitate...

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Detalles Bibliográficos
Autores principales: Liu, Jinxu, Shelkar, Gajanan P., Sarode, Lopmudra P., Gawande, Dinesh Y., Zhao, Fabao, Clausen, Rasmus Praetorius, Ugale, Rajesh R., Dravid, Shashank Manohar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063913/
https://www.ncbi.nlm.nih.gov/pubmed/33421565
http://dx.doi.org/10.1016/j.nbd.2021.105254

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