Soluble Spike DNA Vaccine Provides Long-Term Protective Immunity against SARS-CoV-2 in Mice and Nonhuman Primates

The unprecedented and rapid spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) has motivated the need for a rapidly producible and scalable vaccine. Here, we developed a synthetic soluble SARS-CoV-2 spike (S) DNA-based vaccine candidate, GX-19. In mice, immunization with GX-19 el...

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Detalles Bibliográficos
Autores principales: Seo, Yong Bok, Suh, You Suk, Ryu, Ji In, Jang, Hwanhee, Oh, Hanseul, Koo, Bon-Sang, Seo, Sang-Hwan, Hong, Jung Joo, Song, Manki, Kim, Sung-Joo, Sung, Young Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063950/
https://www.ncbi.nlm.nih.gov/pubmed/33804981
http://dx.doi.org/10.3390/vaccines9040307

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