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miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR/HIF-1α axis

Objectives: Cancer-associated fibroblast (CAF) is among the most important tumor-host microenvironment components by affecting tumor progression. This study explored the role of miR-224 in CAF-induced non-small cell lung cancer (NSCLC). Materials and methods: A CAF-NSCLC cell co-culture model was es...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Han, Lan, Yu, Jing, Li, Hui, Li, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064154/
https://www.ncbi.nlm.nih.gov/pubmed/33819917
http://dx.doi.org/10.18632/aging.202803