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Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury

The regulation of mTOR and the dimethylation of histone H3 on lysine 9 (H3K9me2) H3K9me2 by Uhrf1 and the mechanism of autophagy regulation in myocardial ischemia-reperfusion injury (MIRI) were studied in vivo and in vitro. An in vitro I/R injury model was established using the primary mouse cardiom...

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Detalles Bibliográficos
Autores principales:	Li, Han-Geng, Tian, Wen-Hua, Qin, Cun-Lan, Ye, Rong-Rong, Liu, Dong-Hua, Liu, Hui-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064229/ https://www.ncbi.nlm.nih.gov/pubmed/33744855 http://dx.doi.org/10.18632/aging.202722

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