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Genes and Cancer under Magnetic Control

Many experimental observations convincingly demonstrate that the genes and genome as a whole are sensitive to the magnetic fields, permanent and oscillating. The invasion of nuclear magnetic stable isotopes of Mg, Ca, and Zn in enzymatic catalysis disclosed new features of the DNA and gene chemistry...

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Detalles Bibliográficos
Autores principales: Buchachenko, A. L., Kuznetsov, D. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064421/
http://dx.doi.org/10.1134/S1990793121010024
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author Buchachenko, A. L.
Kuznetsov, D. A.
author_facet Buchachenko, A. L.
Kuznetsov, D. A.
author_sort Buchachenko, A. L.
collection PubMed
description Many experimental observations convincingly demonstrate that the genes and genome as a whole are sensitive to the magnetic fields, permanent and oscillating. The invasion of nuclear magnetic stable isotopes of Mg, Ca, and Zn in enzymatic catalysis disclosed new features of the DNA and gene chemistry; it discovered a new, radical pair mechanism, which substantiated the origin of magnetic effects. This mechanism implies electron transfer between the reaction partners; it is switched on by catalyzing ions and generates magneto-sensitive radical pairs. The key processes of gene functioning – DNA synthesis, DNA damage, and DNA repair – are shown to be magnetically controlled. A new anti-cancer strategy is suggested based on the using of the nuclear magnetic ions of magnesium, calcium, and zinc as a powerful and universal means to selectively kill only cancer cells; they are supposed to be highly promising for medical applications.
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spelling pubmed-80644212021-04-26 Genes and Cancer under Magnetic Control Buchachenko, A. L. Kuznetsov, D. A. Russ. J. Phys. Chem. B Elementary Physicochemical Processes Many experimental observations convincingly demonstrate that the genes and genome as a whole are sensitive to the magnetic fields, permanent and oscillating. The invasion of nuclear magnetic stable isotopes of Mg, Ca, and Zn in enzymatic catalysis disclosed new features of the DNA and gene chemistry; it discovered a new, radical pair mechanism, which substantiated the origin of magnetic effects. This mechanism implies electron transfer between the reaction partners; it is switched on by catalyzing ions and generates magneto-sensitive radical pairs. The key processes of gene functioning – DNA synthesis, DNA damage, and DNA repair – are shown to be magnetically controlled. A new anti-cancer strategy is suggested based on the using of the nuclear magnetic ions of magnesium, calcium, and zinc as a powerful and universal means to selectively kill only cancer cells; they are supposed to be highly promising for medical applications. Pleiades Publishing 2021-04-23 2021 /pmc/articles/PMC8064421/ http://dx.doi.org/10.1134/S1990793121010024 Text en © Pleiades Publishing, Ltd. 2021, ISSN 1990-7931, Russian Journal of Physical Chemistry B, 2021, Vol. 15, No. 1, pp. 1–11. © Pleiades Publishing, Ltd., 2021. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Elementary Physicochemical Processes
Buchachenko, A. L.
Kuznetsov, D. A.
Genes and Cancer under Magnetic Control
title Genes and Cancer under Magnetic Control
title_full Genes and Cancer under Magnetic Control
title_fullStr Genes and Cancer under Magnetic Control
title_full_unstemmed Genes and Cancer under Magnetic Control
title_short Genes and Cancer under Magnetic Control
title_sort genes and cancer under magnetic control
topic Elementary Physicochemical Processes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064421/
http://dx.doi.org/10.1134/S1990793121010024
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