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Efficacy and safety of trifluridine/tipiracil plus bevacizumab and trifluridine/tipiracil or regorafenib monotherapy for chemorefractory metastatic colorectal cancer: a retrospective study

BACKGROUND: The C-TASK-FORCE phase I/II and Danish randomized phase II trials reported the promising efficacy of trifluridine/tipiracil (TAS102) plus bevacizumab (BEV) in patients with chemorefractory metastatic colorectal cancer (mCRC). However, there had been no direct comparative phase III trial...

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Detalles Bibliográficos
Autores principales: Chida, Keigo, Kotani, Daisuke, Nakamura, Yoshiaki, Kawazoe, Akihito, Kuboki, Yasutoshi, Shitara, Kohei, Kojima, Takashi, Taniguchi, Hiroya, Watanabe, Jun, Endo, Itaru, Yoshino, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064512/
https://www.ncbi.nlm.nih.gov/pubmed/33959196
http://dx.doi.org/10.1177/17588359211009143