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Convergent and Divergent Mechanisms of Epileptogenesis in mTORopathies

Hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) due to mutations in genes along the PI3K-mTOR pathway and the GATOR1 complex causes a spectrum of neurodevelopmental disorders (termed mTORopathies) associated with malformation of cortical development and intractable epilepsy...

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Detalles Bibliográficos
Autores principales:	Nguyen, Lena H., Bordey, Angélique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroanatomy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064518/ https://www.ncbi.nlm.nih.gov/pubmed/33897381 http://dx.doi.org/10.3389/fnana.2021.664695

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