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Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy

We measured the overshoot effect in a linac and reduced it using block correction, reverse-sequence correction, and index correction. A StarTrack detector was used on a Varian iX. Five segments, 1 × 10 cm(2) in area, were designed; the centers were at −4, −2, 0, 2, and 4 cm on the x axis for measuri...

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Autores principales: Yu, Chun-Yen, Wan, Shih-Wen, Weng, Yih-Chyang, Hsu, Ching-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064569/
https://www.ncbi.nlm.nih.gov/pubmed/33891639
http://dx.doi.org/10.1371/journal.pone.0250243
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author Yu, Chun-Yen
Wan, Shih-Wen
Weng, Yih-Chyang
Hsu, Ching-Han
author_facet Yu, Chun-Yen
Wan, Shih-Wen
Weng, Yih-Chyang
Hsu, Ching-Han
author_sort Yu, Chun-Yen
collection PubMed
description We measured the overshoot effect in a linac and reduced it using block correction, reverse-sequence correction, and index correction. A StarTrack detector was used on a Varian iX. Five segments, 1 × 10 cm(2) in area, were designed; the centers were at −4, −2, 0, 2, and 4 cm on the x axis for measuring the overshoot effect on a 10 × 10 cm(2) collimator setting. Block correction was applied to two segments. The first was on the new first segment at −6 cm, and the other was on the new last segment at 6 cm. Both two new segments were obtained from the 10 × 10 cm(2) collimator setting. The order of segments was reversed in reverse-sequence correction. Reverse-sequence correction averages the dose at every segment after two irradiations. When we used MLC Shaper, index correction reduced the first segment’s index (cumulative radiation occupation) by 60% and increased the last segment’s radiation occupation by 60% in a new MLC.log file. As for relative dose, the first segment had an overdose of 52.4% and the last segment had an underdose of 48.6%, when irradiated at 1 MU at 600 MU/min. The relative doses at the first segment, irradiated at 1 MU, after block correction, reverse-sequence correction, and index correction were applied decreased from 152.5% to 95.1%, 104.8%, and 100.1%, respectively. The relative doses at the last segment, irradiated at 1 MU, after block correction, reverse-sequence correction, and index correction were applied increased from 48.6% to 97.3%, 91.1%, and 95.9%, respectively. The overshoot effect depended on the speed of irradiation. High irradiation speeds resulted in notable overdosing and underdosing at the first and last segments, respectively. The three corrections mitigated the overshoot effect on dose. To save time and effort, the MLC.log file should be edited with a program in the future.
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spelling pubmed-80645692021-05-04 Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy Yu, Chun-Yen Wan, Shih-Wen Weng, Yih-Chyang Hsu, Ching-Han PLoS One Research Article We measured the overshoot effect in a linac and reduced it using block correction, reverse-sequence correction, and index correction. A StarTrack detector was used on a Varian iX. Five segments, 1 × 10 cm(2) in area, were designed; the centers were at −4, −2, 0, 2, and 4 cm on the x axis for measuring the overshoot effect on a 10 × 10 cm(2) collimator setting. Block correction was applied to two segments. The first was on the new first segment at −6 cm, and the other was on the new last segment at 6 cm. Both two new segments were obtained from the 10 × 10 cm(2) collimator setting. The order of segments was reversed in reverse-sequence correction. Reverse-sequence correction averages the dose at every segment after two irradiations. When we used MLC Shaper, index correction reduced the first segment’s index (cumulative radiation occupation) by 60% and increased the last segment’s radiation occupation by 60% in a new MLC.log file. As for relative dose, the first segment had an overdose of 52.4% and the last segment had an underdose of 48.6%, when irradiated at 1 MU at 600 MU/min. The relative doses at the first segment, irradiated at 1 MU, after block correction, reverse-sequence correction, and index correction were applied decreased from 152.5% to 95.1%, 104.8%, and 100.1%, respectively. The relative doses at the last segment, irradiated at 1 MU, after block correction, reverse-sequence correction, and index correction were applied increased from 48.6% to 97.3%, 91.1%, and 95.9%, respectively. The overshoot effect depended on the speed of irradiation. High irradiation speeds resulted in notable overdosing and underdosing at the first and last segments, respectively. The three corrections mitigated the overshoot effect on dose. To save time and effort, the MLC.log file should be edited with a program in the future. Public Library of Science 2021-04-23 /pmc/articles/PMC8064569/ /pubmed/33891639 http://dx.doi.org/10.1371/journal.pone.0250243 Text en © 2021 Yu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Yu, Chun-Yen
Wan, Shih-Wen
Weng, Yih-Chyang
Hsu, Ching-Han
Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
title Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
title_full Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
title_fullStr Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
title_full_unstemmed Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
title_short Three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
title_sort three corrections for overshoot effect improved the dose for step-and-shoot intensity-modulated radiation therapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064569/
https://www.ncbi.nlm.nih.gov/pubmed/33891639
http://dx.doi.org/10.1371/journal.pone.0250243
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