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Hydraulic resistance induces cell phenotypic transition in confinement

Cells penetrating into confinement undergo mesenchymal-to-amoeboid transition. The topographical features of the microenvironment expose cells to different hydraulic resistance levels. How cells respond to hydraulic resistance is unknown. We show that the cell phenotype shifts from amoeboid to mesen...

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Detalles Bibliográficos
Autores principales: Zhao, Runchen, Cui, Siqi, Ge, Zhuoxu, Zhang, Yuqi, Bera, Kaustav, Zhu, Lily, Sun, Sean X., Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064631/
https://www.ncbi.nlm.nih.gov/pubmed/33893091
http://dx.doi.org/10.1126/sciadv.abg4934