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Hydraulic resistance induces cell phenotypic transition in confinement
Cells penetrating into confinement undergo mesenchymal-to-amoeboid transition. The topographical features of the microenvironment expose cells to different hydraulic resistance levels. How cells respond to hydraulic resistance is unknown. We show that the cell phenotype shifts from amoeboid to mesen...
Autores principales: | Zhao, Runchen, Cui, Siqi, Ge, Zhuoxu, Zhang, Yuqi, Bera, Kaustav, Zhu, Lily, Sun, Sean X., Konstantopoulos, Konstantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064631/ https://www.ncbi.nlm.nih.gov/pubmed/33893091 http://dx.doi.org/10.1126/sciadv.abg4934 |
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