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A non-immunological role for γ-interferon–inducible lysosomal thiol reductase (GILT) in osteoclastic bone resorption
The extracellular bone resorbing lacuna of the osteoclast shares many characteristics with the degradative lysosome of antigen-presenting cells. γ-Interferon–inducible lysosomal thiol reductase (GILT) enhances antigen processing within lysosomes through direct reduction of antigen disulfides and mai...
Autores principales: | Ewanchuk, Benjamin W., Arnold, Corey R., Balce, Dale R., Premnath, Priyatha, Orsetti, Tanis L., Warren, Amy L., Olsen, Alexandra, Krawetz, Roman J., Yates, Robin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064644/ https://www.ncbi.nlm.nih.gov/pubmed/33893096 http://dx.doi.org/10.1126/sciadv.abd3684 |
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