Cargando…

HMGB1/TLR4 Signaling Affects Regulatory T Cells in Acute Lung Injury

BACKGROUND: High-mobility group box-1 protein (HMGB1) serves as the prototypic damage-associated molecular pattern molecule, and TLR4 is considered a receptor for HMGB1. Regulatory T cells (Tregs) play a crucial role in infectious diseases. The role of HMGB1 in the modulation of Tregs is of great in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Min, Zhang, Yadi, Tang, Rui, Liu, Haiyan, Du, Min, Gao, Zhi, Ji, Zongshu, Fang, Haoshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064684/ https://www.ncbi.nlm.nih.gov/pubmed/33907436 http://dx.doi.org/10.2147/JIR.S302967

Ejemplares similares

The Modulation of Regulatory T Cells via HMGB1/PTEN/β-Catenin Axis in LPS Induced Acute Lung Injury
por: Zhou, Min, et al.
Publicado: (2019)

PTEN–Foxo1 signaling triggers HMGB1-mediated innate immune responses in acute lung injury
por: Zhou, Min, et al.
Publicado: (2015)

Glycyrrhizin mitigates radiation‐induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway
por: Zheng, Lei, et al.
Publicado: (2019)

Sesamin attenuates intestinal injury in sepsis via the HMGB1/TLR4/IL-33 signalling pathway
por: Li, Zhi-Ling, et al.
Publicado: (2020)

Potential regulatory role of the Nrf2/HMGB1/TLR4/NF-κB signaling pathway in lupus nephritis
por: Li, Shi-jie, et al.
Publicado: (2023)

TLR4 as receptor for HMGB1-mediated acute lung injury after liver ischemia/reperfusion injury
por: Yang, Zhongwei, et al.
Publicado: (2013)

Inhibition of inflammatory liver injury by the HMGB1-A box through HMGB1/TLR-4/NF-κB signaling in an acute liver failure mouse model
por: Luo, Lidan, et al.
Publicado: (2022)

The role of dendritic cells regulated by HMGB1/TLR4 signalling pathway in myocardial ischaemia reperfusion injury
por: Xue, Jiyang, et al.
Publicado: (2019)

The HMGB1-RAGE/TLR-TNF-α signaling pathway may contribute to kidney injury induced by hypoxia
por: Zhang, Cheng, et al.
Publicado: (2019)

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling
por: Yang, Huan, et al.
Publicado: (2015)

Glycyrrhetinic acid alleviates hepatic inflammation injury in viral hepatitis disease via a HMGB1-TLR4 signaling pathway
por: Shi, Xiaodong, et al.
Publicado: (2020)

A microsatellite DNA-derived oligodeoxynucleotide attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting the HMGB1-TLR4-NF-κB signaling pathway
por: Zhang, Chenghua, et al.
Publicado: (2022)

Oxidation of HMGB1 Causes Attenuation of Its Pro-Inflammatory Activity and Occurs during Liver Ischemia and Reperfusion
por: Liu, Anding, et al.
Publicado: (2012)

TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis
por: Liu, Fang-Yuan, et al.
Publicado: (2019)

IL-1β/HMGB1 signalling promotes the inflammatory cytokines release via TLR signalling in human intervertebral disc cells
por: Fang, Fang, et al.
Publicado: (2016)

THE ALARMIN EFFECT OF HMGB1/RIP3 ON TRANSFUSION-RELATED ACUTE LUNG INJURY VIA TLR4/NF-ΚB OR MAPK PATHWAY
por: Liu, Shuangchun, et al.
Publicado: (2023)

Fibroblast growth factor 10 alleviates particulate matter-induced lung injury by inhibiting the HMGB1-TLR4 pathway
por: Liu, Lingjing, et al.
Publicado: (2020)

Ma Xing Shi Gan Decoction Attenuates PM2.5 Induced Lung Injury via Inhibiting HMGB1/TLR4/NFκB Signal Pathway in Rat
por: Fei, Yu-xiang, et al.
Publicado: (2019)

Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways
por: Yu, Zhuang, et al.
Publicado: (2017)

HMGB1 is a Potential Mediator of Astrocytic TLR4 Signaling Activation following Acute and Chronic Focal Cerebral Ischemia
por: Famakin, Bolanle M., et al.
Publicado: (2020)

The Repression of the HMGB1-TLR4-NF-κB Signaling Pathway by Safflower Yellow May Improve Spinal Cord Injury
por: Wang, Lu, et al.
Publicado: (2021)

Alcohol Induces Zebrafish Skeletal Muscle Atrophy through HMGB1/TLR4/NF-κB Signaling
por: Wen, Wei, et al.
Publicado: (2022)

Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis
por: Chen, Xuelian, et al.
Publicado: (2018)

Glycyrrhizin Ameliorates Radiation Enteritis in Mice Accompanied by the Regulation of the HMGB1/TLR4 Pathway
por: Zhang, Xiao-min, et al.
Publicado: (2020)

Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling
por: Guo, Qingling, et al.
Publicado: (2021)

TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis
por: LI, GANG, et al.
Publicado: (2016)

TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis
por: Li, Gang, et al.
Publicado: (2016)

Extracellular HMGB1 Induced Glomerular Endothelial Cell Injury via TLR4/MyD88 Signaling Pathway in Lupus Nephritis
por: Yu, Tian, et al.
Publicado: (2021)

Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis
por: Akbar, Moeed, et al.
Publicado: (2017)

Tanshinone IIA Downregulates HMGB1 and TLR4 Expression in a Spinal Nerve Ligation Model of Neuropathic Pain
por: Ma, Yu-Qing, et al.
Publicado: (2014)

Metformin attenuates post‐epidural fibrosis by inhibiting the TGF‐β1/Smad3 and HMGB1/TLR4 signaling pathways
por: Song, Zeyuan, et al.
Publicado: (2021)

HMGB1 participates in LPS-induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF-κB signaling pathways
por: Wang, Jing, et al.
Publicado: (2020)

HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury
por: He, Min, et al.
Publicado: (2013)

Phosphoproteome profiling provides insight into the mechanisms of ventilator-induced lung injury
por: Ren, Rongrong, et al.
Publicado: (2020)

Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway
por: Zhang, Jing-jing, et al.
Publicado: (2017)

Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis
por: Zhang, Shilong, et al.
Publicado: (2020)

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression
por: Curtin, James F, et al.
Publicado: (2009)

Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II
por: Zhang, Zhongbin, et al.
Publicado: (2018)

Mechanical Ventilation Enhances HMGB1 Expression in an LPS-Induced Lung Injury Model
por: Ding, Ning, et al.
Publicado: (2013)

HMGB1 and injury amplification
por: Huebener, Peter, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_s731ovg1ea4djhe12semki3mi7