Lipid Metabolism Profiles in Rheumatic Diseases

Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabo...

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Autores principales: Chen, Weilin, Wang, Qi, Zhou, Bin, Zhang, Lihua, Zhu, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064727/
https://www.ncbi.nlm.nih.gov/pubmed/33897433
http://dx.doi.org/10.3389/fphar.2021.643520
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author Chen, Weilin
Wang, Qi
Zhou, Bin
Zhang, Lihua
Zhu, Honglin
author_facet Chen, Weilin
Wang, Qi
Zhou, Bin
Zhang, Lihua
Zhu, Honglin
author_sort Chen, Weilin
collection PubMed
description Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabolism plays important roles in the pathogenesis of rheumatic diseases. In this review, we mainly focus on lipid metabolism profiles (dyslipidaemia, fatty acid metabolism) and mechanisms in rheumatic diseases and discuss potential clinical applications based on lipid metabolism profiles.
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spelling pubmed-80647272021-04-24 Lipid Metabolism Profiles in Rheumatic Diseases Chen, Weilin Wang, Qi Zhou, Bin Zhang, Lihua Zhu, Honglin Front Pharmacol Pharmacology Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabolism plays important roles in the pathogenesis of rheumatic diseases. In this review, we mainly focus on lipid metabolism profiles (dyslipidaemia, fatty acid metabolism) and mechanisms in rheumatic diseases and discuss potential clinical applications based on lipid metabolism profiles. Frontiers Media S.A. 2021-04-09 /pmc/articles/PMC8064727/ /pubmed/33897433 http://dx.doi.org/10.3389/fphar.2021.643520 Text en Copyright © 2021 Chen, Wang, Zhou, Zhang and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Chen, Weilin
Wang, Qi
Zhou, Bin
Zhang, Lihua
Zhu, Honglin
Lipid Metabolism Profiles in Rheumatic Diseases
title Lipid Metabolism Profiles in Rheumatic Diseases
title_full Lipid Metabolism Profiles in Rheumatic Diseases
title_fullStr Lipid Metabolism Profiles in Rheumatic Diseases
title_full_unstemmed Lipid Metabolism Profiles in Rheumatic Diseases
title_short Lipid Metabolism Profiles in Rheumatic Diseases
title_sort lipid metabolism profiles in rheumatic diseases
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064727/
https://www.ncbi.nlm.nih.gov/pubmed/33897433
http://dx.doi.org/10.3389/fphar.2021.643520
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AT wangqi lipidmetabolismprofilesinrheumaticdiseases
AT zhoubin lipidmetabolismprofilesinrheumaticdiseases
AT zhanglihua lipidmetabolismprofilesinrheumaticdiseases
AT zhuhonglin lipidmetabolismprofilesinrheumaticdiseases

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