Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates

In humans, intradermal administration of β-alanine (ALA) and bovine adrenal medulla peptide 8–22 (BAM8-22) evokes the sensation of itch. Currently, it is unknown which human dorsal root ganglion (DRG) neurons express the receptors of these pruritogens, MRGPRD and MRGPRX1, respectively, and which cut...

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Detalles Bibliográficos
Autores principales: Klein, Amanda, Solinski, Hans Jürgen, Malewicz, Nathalie M, Ieong, Hada Fong-ha, Sypek, Elizabeth I, Shimada, Steven G, Hartke, Timothy V, Wooten, Matthew, Wu, Gang, Dong, Xinzhong, Hoon, Mark A, LaMotte, Robert H, Ringkamp, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064749/
https://www.ncbi.nlm.nih.gov/pubmed/33891544
http://dx.doi.org/10.7554/eLife.64506

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