Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2

It is unclear whether individuals with enormous diversity in B cell receptor repertoires are consistently able to mount effective antibody responses against SARS-CoV-2. We analyzed antibody responses in a cohort of 55 convalescent patients and isolated 54 potent neutralizing monoclonal antibodies (m...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaojuan, Ma, Fengge, Xie, Jun, Yuan, Meng, Li, Yunqiao, Shaabani, Namir, Zhao, Fangzhu, Huang, Deli, Wu, Nicholas C., Lee, Chang-Chun D., Liu, Hejun, Li, Jiali, Chen, Zhonghui, Hong, Yazhen, Liu, Wen-Hsien, Xiao, Nengming, Burton, Dennis R., Tu, Haijian, Li, Hang, Chen, Xin, Teijaro, John R., Wilson, Ian A., Xiao, Changchun, Huang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064889/
https://www.ncbi.nlm.nih.gov/pubmed/33932326
http://dx.doi.org/10.1016/j.celrep.2021.109109

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