Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein

Patients who recover from SARS-CoV-2 infections produce antibodies and antigen-specific T cells against multiple viral proteins. Here, an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent patients has been performed by generating large, stable hybridoma libraries and...

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Detalles Bibliográficos
Autores principales: DiMuzio, Jillian M., Heimbach, Baron C., Howanski, Raymond J., Dowling, John P., Patel, Nirja B., Henriquez, Noeleya, Nicolescu, Chris, Nath, Mitchell, Polley, Antonio, Bingaman, Jamie L., Smith, Todd, Harman, Benjamin C., Robinson, Matthew K., Morin, Michael J., Nikitin, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064894/
https://www.ncbi.nlm.nih.gov/pubmed/33937741
http://dx.doi.org/10.1016/j.jvacx.2021.100098

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