Cargando…

How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA

Bacteriophages have long been known to use modified bases in their DNA to prevent cleavage by the host’s restriction endonucleases. Among them, cyanophage S-2L is unique because its genome has all its adenines (A) systematically replaced by 2-aminoadenines (Z). Here, we identify a member of the Prim...

Descripción completa

Detalles Bibliográficos
Autores principales: Czernecki, Dariusz, Legrand, Pierre, Tekpinar, Mustafa, Rosario, Sandrine, Kaminski, Pierre-Alexandre, Delarue, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065100/
https://www.ncbi.nlm.nih.gov/pubmed/33893297
http://dx.doi.org/10.1038/s41467-021-22626-x