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Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses

Rare protein-truncating variants (PTVs) in PALB2 confer increased risk to breast cancer, but relatively few studies have reported the characteristics of tumours with PALB2 PTVs. In this study, we describe molecular characteristics of tumours with either germline or somatic alterations in PALB2. DNA...

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Detalles Bibliográficos
Autores principales:	Ng, Pei Sze, Pan, Jia Wern, Ahmad Zabidi, Muhammad Mamduh, Rajadurai, Pathmanathan, Yip, Cheng Har, Reuda, Oscar M., Dunning, Alison M., Antoniou, Antonis C., Easton, Douglas F., Caldas, Carlos, Chin, Suet-Feung, Teo, Soo Hwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065101/ https://www.ncbi.nlm.nih.gov/pubmed/33893315 http://dx.doi.org/10.1038/s41523-021-00254-4

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