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Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells
Arginine plays diverse roles in cellular physiology. As a semi-essential amino acid, arginine deprivation has been used to target cancers with arginine synthesis deficiency. Arginine-deprived cancer cells exhibit mitochondrial dysfunction, transcriptional reprogramming and eventual cell death. In th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065123/ https://www.ncbi.nlm.nih.gov/pubmed/33893278 http://dx.doi.org/10.1038/s41467-021-22652-9 |