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BBSome ablation in SF1 neurons causes obesity without comorbidities
OBJECTIVES: The hypothalamic ventromedial nucleus (VMH) plays a major role in metabolic control, but the molecular mechanisms involved remain poorly defined. We analyzed the relevance of the BBSome, a protein complex composed of 8 Bardet–Biedl syndrome (BBS) proteins including BBS1, in VMH steroidog...
Autores principales: | Rouabhi, Mohamed, Guo, Deng-Fu, Morgan, Donald A., Zhu, Zhiyong, López, Miguel, Zingman, Leonid, Grobe, Justin L., Rahmouni, Kamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065214/ https://www.ncbi.nlm.nih.gov/pubmed/33722691 http://dx.doi.org/10.1016/j.molmet.2021.101211 |
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