HIV-based lentiviral vectors: origin and sequence differences

Three gene therapy strategies have received US Food and Drug Administration (FDA) approval; one includes HIV-1-based lentiviral vectors. These vectors incorporate features to provide long-term gene transfer and expression while minimizing generation of a replication-competent virus or pathogenicity....

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Detalles Bibliográficos
Autores principales: Johnson, Nathan M., Alvarado, Anna Francesca, Moffatt, Trey N., Edavettal, Joshua M., Swaminathan, Tarun A., Braun, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065252/
https://www.ncbi.nlm.nih.gov/pubmed/33981779
http://dx.doi.org/10.1016/j.omtm.2021.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065252/
https://www.ncbi.nlm.nih.gov/pubmed/33981779
http://dx.doi.org/10.1016/j.omtm.2021.03.018

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