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ICOS signaling limits regulatory T cell accumulation and function in visceral adipose tissue

A unique population of Foxp3(+) regulatory T cells (T(R)s) resides in visceral adipose tissue (VAT) that regulates adipose inflammation and helps preserve insulin sensitivity. Inducible T cell co-stimulator (ICOS) is highly expressed on effector (e)T(R)s that migrate to nonlymphoid tissues, and cont...

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Detalles Bibliográficos
Autores principales:	Mittelsteadt, Kristen L., Hayes, Erika T., Campbell, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065270/ https://www.ncbi.nlm.nih.gov/pubmed/33881452 http://dx.doi.org/10.1084/jem.20201142

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