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Combined RT-qPCR and pyrosequencing of a Spike glycoprotein polybasic cleavage motif can uncover pediatric SARS-CoV-2 infections associated with heterogeneous presentation

BACKGROUND: Reverse transcription of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (+)RNA genome and subgenomic RNAs (sgRNAs) and subsequent quantitative polymerase chain reaction (RT-qPCR) is the reliable diagnostic gold standard for COVID-19 diagnosis and the identification of p...

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Detalles Bibliográficos
Autores principales:	Weil, Patrick Philipp, Hentschel, Jacqueline, Schult, Frank, Pembaur, Anton, Ghebremedhin, Beniam, Mboma, Olivier, Heusch, Andreas, Reuter, Anna-Christin, Müller, Daniel, Wirth, Stefan, Aydin, Malik, Jenke, Andreas C. W., Postberg, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065314/ https://www.ncbi.nlm.nih.gov/pubmed/33893880 http://dx.doi.org/10.1186/s40348-021-00115-x

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