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The Biomechanics of Cartilage—An Overview
Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficia...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065530/ https://www.ncbi.nlm.nih.gov/pubmed/33915881 http://dx.doi.org/10.3390/life11040302 |
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author | Eschweiler, Joerg Horn, Nils Rath, Bjoern Betsch, Marcel Baroncini, Alice Tingart, Markus Migliorini, Filippo |
author_facet | Eschweiler, Joerg Horn, Nils Rath, Bjoern Betsch, Marcel Baroncini, Alice Tingart, Markus Migliorini, Filippo |
author_sort | Eschweiler, Joerg |
collection | PubMed |
description | Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficial (tangential) zone, middle (transitional) zone, deep zone, calcified zone) with different mechanical properties. An overview is given about different testing (load tests) methods as well as different modeling approaches. The widely accepted biomechanical test methods, e.g., the indentation analysis, are summarized and discussed. A description of the biphasic theory is also shown. This is required to understand how interstitial water contributes toward the viscoelastic behavior of AC. Furthermore, a short introduction to a more complex model is given. |
format | Online Article Text |
id | pubmed-8065530 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80655302021-04-25 The Biomechanics of Cartilage—An Overview Eschweiler, Joerg Horn, Nils Rath, Bjoern Betsch, Marcel Baroncini, Alice Tingart, Markus Migliorini, Filippo Life (Basel) Review Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficial (tangential) zone, middle (transitional) zone, deep zone, calcified zone) with different mechanical properties. An overview is given about different testing (load tests) methods as well as different modeling approaches. The widely accepted biomechanical test methods, e.g., the indentation analysis, are summarized and discussed. A description of the biphasic theory is also shown. This is required to understand how interstitial water contributes toward the viscoelastic behavior of AC. Furthermore, a short introduction to a more complex model is given. MDPI 2021-04-01 /pmc/articles/PMC8065530/ /pubmed/33915881 http://dx.doi.org/10.3390/life11040302 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Eschweiler, Joerg Horn, Nils Rath, Bjoern Betsch, Marcel Baroncini, Alice Tingart, Markus Migliorini, Filippo The Biomechanics of Cartilage—An Overview |
title | The Biomechanics of Cartilage—An Overview |
title_full | The Biomechanics of Cartilage—An Overview |
title_fullStr | The Biomechanics of Cartilage—An Overview |
title_full_unstemmed | The Biomechanics of Cartilage—An Overview |
title_short | The Biomechanics of Cartilage—An Overview |
title_sort | biomechanics of cartilage—an overview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065530/ https://www.ncbi.nlm.nih.gov/pubmed/33915881 http://dx.doi.org/10.3390/life11040302 |
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