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The Biomechanics of Cartilage—An Overview

Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficia...

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Autores principales: Eschweiler, Joerg, Horn, Nils, Rath, Bjoern, Betsch, Marcel, Baroncini, Alice, Tingart, Markus, Migliorini, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065530/
https://www.ncbi.nlm.nih.gov/pubmed/33915881
http://dx.doi.org/10.3390/life11040302
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author Eschweiler, Joerg
Horn, Nils
Rath, Bjoern
Betsch, Marcel
Baroncini, Alice
Tingart, Markus
Migliorini, Filippo
author_facet Eschweiler, Joerg
Horn, Nils
Rath, Bjoern
Betsch, Marcel
Baroncini, Alice
Tingart, Markus
Migliorini, Filippo
author_sort Eschweiler, Joerg
collection PubMed
description Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficial (tangential) zone, middle (transitional) zone, deep zone, calcified zone) with different mechanical properties. An overview is given about different testing (load tests) methods as well as different modeling approaches. The widely accepted biomechanical test methods, e.g., the indentation analysis, are summarized and discussed. A description of the biphasic theory is also shown. This is required to understand how interstitial water contributes toward the viscoelastic behavior of AC. Furthermore, a short introduction to a more complex model is given.
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spelling pubmed-80655302021-04-25 The Biomechanics of Cartilage—An Overview Eschweiler, Joerg Horn, Nils Rath, Bjoern Betsch, Marcel Baroncini, Alice Tingart, Markus Migliorini, Filippo Life (Basel) Review Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficial (tangential) zone, middle (transitional) zone, deep zone, calcified zone) with different mechanical properties. An overview is given about different testing (load tests) methods as well as different modeling approaches. The widely accepted biomechanical test methods, e.g., the indentation analysis, are summarized and discussed. A description of the biphasic theory is also shown. This is required to understand how interstitial water contributes toward the viscoelastic behavior of AC. Furthermore, a short introduction to a more complex model is given. MDPI 2021-04-01 /pmc/articles/PMC8065530/ /pubmed/33915881 http://dx.doi.org/10.3390/life11040302 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Eschweiler, Joerg
Horn, Nils
Rath, Bjoern
Betsch, Marcel
Baroncini, Alice
Tingart, Markus
Migliorini, Filippo
The Biomechanics of Cartilage—An Overview
title The Biomechanics of Cartilage—An Overview
title_full The Biomechanics of Cartilage—An Overview
title_fullStr The Biomechanics of Cartilage—An Overview
title_full_unstemmed The Biomechanics of Cartilage—An Overview
title_short The Biomechanics of Cartilage—An Overview
title_sort biomechanics of cartilage—an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065530/
https://www.ncbi.nlm.nih.gov/pubmed/33915881
http://dx.doi.org/10.3390/life11040302
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