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Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score

Background and Objectives: Unicompartmental knee arthroplasty (UKA) is a valid alternative to total knee arthroplasties (TKAs) in selected cases. After surgery, patients’ experience and satisfaction were traditionally evaluated by pre- and postsurgical scores and Patient-Reported Outcome Measures (P...

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Autores principales: Longo, Umile Giuseppe, De Salvatore, Sergio, Candela, Vincenzo, Berton, Alessandra, Casciaro, Carlo, Sciotti, Gaia, Cirimele, Giada, Marchetti, Anna, Piergentili, Ilaria, De Marinis, Maria Grazia, Denaro, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065647/
https://www.ncbi.nlm.nih.gov/pubmed/33915704
http://dx.doi.org/10.3390/medicina57040324
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author Longo, Umile Giuseppe
De Salvatore, Sergio
Candela, Vincenzo
Berton, Alessandra
Casciaro, Carlo
Sciotti, Gaia
Cirimele, Giada
Marchetti, Anna
Piergentili, Ilaria
De Marinis, Maria Grazia
Denaro, Vincenzo
author_facet Longo, Umile Giuseppe
De Salvatore, Sergio
Candela, Vincenzo
Berton, Alessandra
Casciaro, Carlo
Sciotti, Gaia
Cirimele, Giada
Marchetti, Anna
Piergentili, Ilaria
De Marinis, Maria Grazia
Denaro, Vincenzo
author_sort Longo, Umile Giuseppe
collection PubMed
description Background and Objectives: Unicompartmental knee arthroplasty (UKA) is a valid alternative to total knee arthroplasties (TKAs) in selected cases. After surgery, patients’ experience and satisfaction were traditionally evaluated by pre- and postsurgical scores and Patient-Reported Outcome Measures (PROMs). Otherwise, a statistically significant change does not necessarily correlate to a clinically meaningful improvement when measured using PROMs. To evaluate the real effect of a specific treatment and understand the difference between groups in a clinical trial, it is necessary to use a meaningful quantum of change on the score assessed. The minimal clinically important difference (MCID) and the Patient Acceptable Symptom State (PASS) can provide this meaningful change. This paper aimed to calculate the MCID and the PASS of the Forgotten Joint Score (FJS-12) after UKA. Materials and Methods: A total of 40 patients with a mean age 72.5 ± 6.4 years undergoing UKA were assessed preoperatively and six months postsurgery using the FJS-12 and the Oxford Knee Score (OKS). The baseline and 6-month postoperative scores were compared using the Wilcoxon signed ranks test. The correlation was calculated with Spearman’s rho. Both distribution-based approaches and anchor approaches were used to estimate MCID for the FJS-12. The 75th percentile and the Receiver operating characteristic (ROC) curve methods were used to calculate the PASS of FJS-12. Results: MCID estimates for normalized FJS-12 for UKA ranged from 5.68 to 19.82. The threshold of the FJS-12 with ROC method was 72.92 (AUC = 0.76). The cut-off value computed with the 75th percentile approach was 92.71. Conclusions: The MCID and PASS represent valid tools to assess the real perception of clinical improvement in patients who underwent UKA. The MCID value of FJS-12 was 12.5 for patients who underwent UKA. The value of the PASS for the FJS-12 in patients who underwent UKA was 72.92.
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spelling pubmed-80656472021-04-25 Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score Longo, Umile Giuseppe De Salvatore, Sergio Candela, Vincenzo Berton, Alessandra Casciaro, Carlo Sciotti, Gaia Cirimele, Giada Marchetti, Anna Piergentili, Ilaria De Marinis, Maria Grazia Denaro, Vincenzo Medicina (Kaunas) Article Background and Objectives: Unicompartmental knee arthroplasty (UKA) is a valid alternative to total knee arthroplasties (TKAs) in selected cases. After surgery, patients’ experience and satisfaction were traditionally evaluated by pre- and postsurgical scores and Patient-Reported Outcome Measures (PROMs). Otherwise, a statistically significant change does not necessarily correlate to a clinically meaningful improvement when measured using PROMs. To evaluate the real effect of a specific treatment and understand the difference between groups in a clinical trial, it is necessary to use a meaningful quantum of change on the score assessed. The minimal clinically important difference (MCID) and the Patient Acceptable Symptom State (PASS) can provide this meaningful change. This paper aimed to calculate the MCID and the PASS of the Forgotten Joint Score (FJS-12) after UKA. Materials and Methods: A total of 40 patients with a mean age 72.5 ± 6.4 years undergoing UKA were assessed preoperatively and six months postsurgery using the FJS-12 and the Oxford Knee Score (OKS). The baseline and 6-month postoperative scores were compared using the Wilcoxon signed ranks test. The correlation was calculated with Spearman’s rho. Both distribution-based approaches and anchor approaches were used to estimate MCID for the FJS-12. The 75th percentile and the Receiver operating characteristic (ROC) curve methods were used to calculate the PASS of FJS-12. Results: MCID estimates for normalized FJS-12 for UKA ranged from 5.68 to 19.82. The threshold of the FJS-12 with ROC method was 72.92 (AUC = 0.76). The cut-off value computed with the 75th percentile approach was 92.71. Conclusions: The MCID and PASS represent valid tools to assess the real perception of clinical improvement in patients who underwent UKA. The MCID value of FJS-12 was 12.5 for patients who underwent UKA. The value of the PASS for the FJS-12 in patients who underwent UKA was 72.92. MDPI 2021-04-01 /pmc/articles/PMC8065647/ /pubmed/33915704 http://dx.doi.org/10.3390/medicina57040324 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Longo, Umile Giuseppe
De Salvatore, Sergio
Candela, Vincenzo
Berton, Alessandra
Casciaro, Carlo
Sciotti, Gaia
Cirimele, Giada
Marchetti, Anna
Piergentili, Ilaria
De Marinis, Maria Grazia
Denaro, Vincenzo
Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score
title Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score
title_full Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score
title_fullStr Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score
title_full_unstemmed Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score
title_short Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient Acceptable Symptom State for the Forgotten Joint Score
title_sort unicompartmental knee arthroplasty: minimal important difference and patient acceptable symptom state for the forgotten joint score
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065647/
https://www.ncbi.nlm.nih.gov/pubmed/33915704
http://dx.doi.org/10.3390/medicina57040324
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