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Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway

Most human cancers circumvent senescence by activating a telomere length maintenance mechanism, most commonly involving telomerase activation. A minority of cancers utilize the recombination-based alternative lengthening of telomeres (ALT) pathway. The exact requirements for unleashing normally repr...

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Detalles Bibliográficos
Autores principales: Toubiana, Shir, Tzur-Gilat, Aya, Selig, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065733/
https://www.ncbi.nlm.nih.gov/pubmed/33810393
http://dx.doi.org/10.3390/life11040278

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