Sir4 Deficiency Reverses Cell Senescence by Sub-Telomere Recombination

Telomere shortening results in cellular senescence and the regulatory mechanisms remain unclear. Here, we report that the sub-telomere regions facilitate telomere lengthening by homologous recombination, thereby attenuating senescence in yeast Saccharomyces cerevisiae. The telomere protein complex S...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Hong, Xiaojing, Wang, Lihui, Liang, Chao-Ya, Liu, Jun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066019/
https://www.ncbi.nlm.nih.gov/pubmed/33915984
http://dx.doi.org/10.3390/cells10040778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066019/
https://www.ncbi.nlm.nih.gov/pubmed/33915984
http://dx.doi.org/10.3390/cells10040778

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