Cargando…

Diverse Regulation but Conserved Function: SOX9 in Vertebrate Sex Determination

Sex determination occurs early during embryogenesis among vertebrates. It involves the differentiation of the bipotential gonad to ovaries or testes by a fascinating diversity of molecular switches. In most mammals, the switch is SRY (sex determining region Y); in other vertebrates it could be one o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vining, Brittany, Ming, Zhenhua, Bagheri-Fam, Stefan, Harley, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066042/ https://www.ncbi.nlm.nih.gov/pubmed/33810596 http://dx.doi.org/10.3390/genes12040486

Ejemplares similares

SOX9 in organogenesis: shared and unique transcriptional functions
por: Ming, Zhenhua, et al.
Publicado: (2022)

Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations
por: Knower, Kevin C., et al.
Publicado: (2011)

Dataset of differentially expressed genes from SOX9 over-expressing NT2/D1 cells
por: Ludbrook, Louisa, et al.
Publicado: (2016)

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures
por: Rahmoun, Massilva, et al.
Publicado: (2017)

The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming
por: Lindeman, Robin E, et al.
Publicado: (2021)

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9
por: Croft, Brittany, et al.
Publicado: (2018)

Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9
por: Croft, Brittany, et al.
Publicado: (2019)

Up-regulation of sex-determining region Y-box 9 (SOX9) in growth hormone-secreting pituitary adenomas
por: Shirian, Farzad Izak, et al.
Publicado: (2021)

Dataset of differentially expressed genes in mouse P12 testes in response to the loss of ATRX in Sertoli cells
por: Bagheri-Fam, Stefan, et al.
Publicado: (2022)

Mutations in the Testis-Specific Enhancer of SOX9 in the SRY Independent Sex-Determining Mechanism in the Genus Tokudaia
por: Kimura, Ryutaro, et al.
Publicado: (2014)

Divergent Expression Regulation of Gonad Development Genes in Medaka Shows Incomplete Conservation of the Downstream Regulatory Network of Vertebrate Sex Determination
por: Herpin, Amaury, et al.
Publicado: (2013)

The Variety of Vertebrate Mechanisms of Sex Determination
por: Trukhina, Antonina V., et al.
Publicado: (2013)

Sex, Sox, and splicing
por: LeBrasseur, Nicole
Publicado: (2002)

Linking physiological approaches to marine vertebrate conservation: using sex steroid hormone determinations in demographic assessments
por: Labrada-Martagón, Vanessa, et al.
Publicado: (2014)

Upregulation of sex-determining region Y-box 9 (SOX9) promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma
por: Hong, Yingcai, et al.
Publicado: (2015)

Sox9 is indispensable for testis differentiation in the red-eared slider turtle, a reptile with temperature-dependent sex determination
por: Hui, Hang-Bo, et al.
Publicado: (2021)

Molecular evolution of vertebrate sex-determining genes
por: Mawaribuchi, Shuuji, et al.
Publicado: (2011)

Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9
por: Geraldo, Marcos Tadeu, et al.
Publicado: (2016)

SOX2-Sensing: Insights into the Role of SOX2 in the Generation of Sensory Cell Types in Vertebrates
por: Mercurio, Sara
Publicado: (2023)

Genomic Analysis of the Pacific Oyster (Crassostrea gigas) Reveals Possible Conservation of Vertebrate Sex Determination in a Mollusc
por: Zhang, Na, et al.
Publicado: (2014)

Master-Key Regulators of Sex Determination in Fish and Other Vertebrates—A Review
por: Curzon, Arie Yehuda, et al.
Publicado: (2023)

Sox9 is required for prostate development and prostate cancer initiation
por: Huang, Zhenhua, et al.
Publicado: (2012)

SOX9 is a dose-dependent metastatic fate determinant in melanoma
por: Yang, Xintao, et al.
Publicado: (2019)

Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5
por: Hattori, Takako, et al.
Publicado: (2008)

Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma
por: Shakhova, Olga, et al.
Publicado: (2015)

Global determinants and conservation of evolutionary and geographic rarity in land vertebrates
por: Murali, Gopal, et al.
Publicado: (2021)

Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals
por: Richardson, Nainoa, et al.
Publicado: (2020)

Vertebrate sex-determining genes play musical chairs
por: Pan, Qiaowei, et al.
Publicado: (2016)

Analysis of Medaka sox9 Orthologue Reveals a Conserved Role in Germ Cell Maintenance
por: Nakamura, Shuhei, et al.
Publicado: (2012)

Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells in a specific manner and regulated by SOX9 during testicular development
por: Tsuji-Hosokawa, Atsumi, et al.
Publicado: (2018)

The SOXE transcription factors—SOX8, SOX9 and SOX10—share a bi-partite transactivation mechanism
por: Haseeb, Abdul, et al.
Publicado: (2019)

The Amphioxus SoxB Family: Implications for the Evolution of Vertebrate Placodes
por: Meulemans, Daniel, et al.
Publicado: (2007)

Mechanical force regulates Sox9 expression at the developing enthesis
por: Subramanian, Arul, et al.
Publicado: (2023)

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates
por: Baker, Zachary, et al.
Publicado: (2017)

Lipid availability determines skeletal progenitor cell fate via SOX9
por: van Gastel, Nick, et al.
Publicado: (2020)

Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
por: Stüfchen, Isabel, et al.
Publicado: (2023)

RevSex duplication-induced and sex-related differences in the SOX9 regulatory region chromatin landscape in human fibroblasts
por: Lybæk, Helle, et al.
Publicado: (2014)

Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis
por: Werner, Torsten, et al.
Publicado: (2007)

Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken
por: Yamashita, Satoshi, et al.
Publicado: (2019)

Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements
por: Schartl, Manfred, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_p0apcifuporpslmeqp6c5jvioa