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Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital
Clinical trials in cancer treatment are imperative in enhancing patients’ survival and quality of life outcomes. The lack of communication among professionals may produce a non-optimization of patients’ accrual in clinical trials. We developed a specific platform, called “Digital Research Assistant”...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066078/ https://www.ncbi.nlm.nih.gov/pubmed/33801668 http://dx.doi.org/10.3390/jpm11040244 |
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author | Cesario, Alfredo Simone, Irene Paris, Ida Boldrini, Luca Orlandi, Armando Franceschini, Gianluca Lococo, Filippo Bria, Emilio Magno, Stefano Mulè, Antonino Santoro, Angela Damiani, Andrea Bianchi, Daniele Picchi, Daniele Rasi, Guido Daniele, Gennaro Fabi, Alessandra Sergi, Paolo Tortora, Giampaolo Masetti, Riccardo Valentini, Vincenzo D’Oria, Marika Scambia, Giovanni |
author_facet | Cesario, Alfredo Simone, Irene Paris, Ida Boldrini, Luca Orlandi, Armando Franceschini, Gianluca Lococo, Filippo Bria, Emilio Magno, Stefano Mulè, Antonino Santoro, Angela Damiani, Andrea Bianchi, Daniele Picchi, Daniele Rasi, Guido Daniele, Gennaro Fabi, Alessandra Sergi, Paolo Tortora, Giampaolo Masetti, Riccardo Valentini, Vincenzo D’Oria, Marika Scambia, Giovanni |
author_sort | Cesario, Alfredo |
collection | PubMed |
description | Clinical trials in cancer treatment are imperative in enhancing patients’ survival and quality of life outcomes. The lack of communication among professionals may produce a non-optimization of patients’ accrual in clinical trials. We developed a specific platform, called “Digital Research Assistant” (DRA), to report real-time every available clinical trial and support clinician. Healthcare professionals involved in breast cancer working group agreed nine minimal fields of interest to preliminarily classify the characteristics of patients’ records (including omic data, such as genomic mutations). A progressive web app (PWA) was developed to implement a cross-platform software that was scalable on several electronic devices to share the patients’ records and clinical trials. A specialist is able to use and populate the platform. An AI algorithm helps in the matchmaking between patient’s data and clinical trial’s inclusion criteria to personalize patient enrollment. At the same time, an easy configuration allows the application of the DRA in different oncology working groups (from breast cancer to lung cancer). The DRA might represent a valid research tool supporting clinicians and scientists, in order to optimize the enrollment of patients in clinical trials. User Experience and Technology The acceptance of participants using the DRA is topic of a future analysis. |
format | Online Article Text |
id | pubmed-8066078 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80660782021-04-25 Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital Cesario, Alfredo Simone, Irene Paris, Ida Boldrini, Luca Orlandi, Armando Franceschini, Gianluca Lococo, Filippo Bria, Emilio Magno, Stefano Mulè, Antonino Santoro, Angela Damiani, Andrea Bianchi, Daniele Picchi, Daniele Rasi, Guido Daniele, Gennaro Fabi, Alessandra Sergi, Paolo Tortora, Giampaolo Masetti, Riccardo Valentini, Vincenzo D’Oria, Marika Scambia, Giovanni J Pers Med Article Clinical trials in cancer treatment are imperative in enhancing patients’ survival and quality of life outcomes. The lack of communication among professionals may produce a non-optimization of patients’ accrual in clinical trials. We developed a specific platform, called “Digital Research Assistant” (DRA), to report real-time every available clinical trial and support clinician. Healthcare professionals involved in breast cancer working group agreed nine minimal fields of interest to preliminarily classify the characteristics of patients’ records (including omic data, such as genomic mutations). A progressive web app (PWA) was developed to implement a cross-platform software that was scalable on several electronic devices to share the patients’ records and clinical trials. A specialist is able to use and populate the platform. An AI algorithm helps in the matchmaking between patient’s data and clinical trial’s inclusion criteria to personalize patient enrollment. At the same time, an easy configuration allows the application of the DRA in different oncology working groups (from breast cancer to lung cancer). The DRA might represent a valid research tool supporting clinicians and scientists, in order to optimize the enrollment of patients in clinical trials. User Experience and Technology The acceptance of participants using the DRA is topic of a future analysis. MDPI 2021-03-27 /pmc/articles/PMC8066078/ /pubmed/33801668 http://dx.doi.org/10.3390/jpm11040244 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Article Cesario, Alfredo Simone, Irene Paris, Ida Boldrini, Luca Orlandi, Armando Franceschini, Gianluca Lococo, Filippo Bria, Emilio Magno, Stefano Mulè, Antonino Santoro, Angela Damiani, Andrea Bianchi, Daniele Picchi, Daniele Rasi, Guido Daniele, Gennaro Fabi, Alessandra Sergi, Paolo Tortora, Giampaolo Masetti, Riccardo Valentini, Vincenzo D’Oria, Marika Scambia, Giovanni Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital |
title | Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital |
title_full | Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital |
title_fullStr | Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital |
title_full_unstemmed | Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital |
title_short | Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital |
title_sort | development of a digital research assistant for the management of patients’ enrollment in oncology clinical trials within a research hospital |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066078/ https://www.ncbi.nlm.nih.gov/pubmed/33801668 http://dx.doi.org/10.3390/jpm11040244 |
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