Cargando…
Evaluation of the Effectiveness of Post-Stroke Metformin Treatment Using Permanent Middle Cerebral Artery Occlusion in Rats
Stroke is the second leading cause of death worldwide. Treatment options for ischemic stroke are limited, and the development of new therapeutic agents or combined therapies is imperative. Growing evidence suggests that metformin treatment, due to its anti-inflammatory action, exerts a neuroprotecti...
Autores principales: | Zemgulyte, Gintare, Tanaka, Shigeru, Hide, Izumi, Sakai, Norio, Pampuscenko, Katryna, Borutaite, Vilmante, Rastenyte, Daiva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066143/ https://www.ncbi.nlm.nih.gov/pubmed/33915857 http://dx.doi.org/10.3390/ph14040312 |
Ejemplares similares
-
The Role of Intracellular Ca(2+) and Mitochondrial ROS in Small Aβ(1-42) Oligomer-Induced Microglial Death
por: Jekabsone, Aiste, et al.
Publicado: (2023) -
Extracellular tau stimulates phagocytosis of living neurons by activated microglia via Toll-like 4 receptor–NLRP3 inflammasome–caspase-1 signalling axis
por: Pampuscenko, Katryna, et al.
Publicado: (2023) -
Effects of Metformin on Spontaneous Ca(2+) Signals in Cultured Microglia Cells under Normoxic and Hypoxic Conditions
por: Jankeviciute, Silvija, et al.
Publicado: (2021) -
Comparison of Effects of Metformin, Phenformin, and Inhibitors of Mitochondrial Complex I on Mitochondrial Permeability Transition and Ischemic Brain Injury
por: Skemiene, Kristina, et al.
Publicado: (2020) -
The microglial P2Y(6) receptor mediates neuronal loss and memory deficits in neurodegeneration
por: Puigdellívol, Mar, et al.
Publicado: (2021)